{"title":"MIGRAINE","description":"","products":[{"product_id":"sumatec-tablets-50mg-1-box-1-strip-1-strip-2-tablets","title":"Sumatec Tablets 50mg (1 Box = 1 Strip)(1 Strip = 2 Tablets)","description":"\u003cp\u003eSumatriptan has been demonstrated to be a selective vascular 5-hydroxytryptamine-1-(5-HT 1D) receptor agonist with no effect at other 5-HT receptor (5-HT2–7) subtypes. The vascular 5-HT 1D receptor is found predominantly in cranial blood vessels and mediates vasoconstriction. In animals, sumatriptan selectively constricts the carotid arterial circulation, but does not alter cerebral blood flow. The carotid arterial circulation supplies blood to the extracranial and intracranial tissues such as the meninges and dilatation and\/or oedema formation in these vessels is thought to be the underlying mechanism of migraine in man. In addition, experimental evidence suggests that sumatriptan inhibits trigeminal nerve activity. Both these actions may contribute to the anti-migraine action of sumatriptan in humans.\u003c\/p\u003e","brand":"Platinum Pharmaceutical","offers":[{"title":"Default Title","offer_id":47654691700966,"sku":null,"price":299.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/Sumatec50mgTablets.png?v=1781940093"},{"product_id":"sumoxen-tablets-85-500mg-1-box-1-strip1-strip-2-tablets","title":"Sumoxen Tablets 85\/500mg (1 Box = 1 Strip)(1 Strip = 2 Tablets)","description":"\u003cp\u003eIt contains sumatriptan, a 5-HT1 receptor agonist that mediates vasoconstriction of the human basilar artery and vasculature of human dura mater, which correlates with the relief of migraine headache. It also contains naproxen, an NSAID that inhibits the synthesis of inflammatory mediators. Therefore, sumatriptan and naproxen contribute to the relief of migraine through pharmacologically different mechanisms of action.\u003c\/p\u003e","brand":"Atco Laboratories Limited","offers":[{"title":"Default Title","offer_id":47654691766502,"sku":null,"price":400.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/sumoxen.png?v=1781940182"},{"product_id":"synflex-m-tablets-85mg-550mg-1-box-1-strip1-strip-2-tablets","title":"Synflex-M Tablets 85mg+550mg (1 Box = 1 Strip)(1 Strip = 2 Tablets)","description":"\u003cp\u003eIt contains sumatriptan, a 5-HT1 receptor agonist that mediates vasoconstriction of the human basilar artery and vasculature of human dura mater, which correlates with the relief of migraine headache. It also contains naproxen, an NSAID that inhibits the synthesis of inflammatory mediators. Therefore, sumatriptan and naproxen contribute to the relief of migraine through pharmacologically different mechanisms of action.\u003c\/p\u003e","brand":"Martin Dow","offers":[{"title":"Default Title","offer_id":47654691799270,"sku":null,"price":430.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/synflexm.png?v=1781939738"},{"product_id":"limigzol-tablets-2-5mg-1-box-1-strip-1-strip-10-tablets","title":"Limigzol Tablets 2.5mg (1 Box = 1 Strip)(1 Strip = 10 Tablets)","description":"\u003cp\u003eMigraine symptoms may be caused by swollen blood vessels in the head. It is thought to reduce the widening of these blood vessels. This helps to take away the headache and other symptoms of a migraine attack, such as feeling of being sick (nausea or vomiting) and being sensitive to light and sound.\u003c\/p\u003e","brand":"Genetics Pharmaceuticals Pvt Ltd","offers":[{"title":"Default Title","offer_id":47654691864806,"sku":null,"price":1150.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/limigzol.png?v=1781939878"},{"product_id":"triptan-tablets-2-5mg-1-box-1-strip-1-strip-3-tablets","title":"Triptan Tablets 2.5mg (1 Box = 1 Strip)(1 Strip = 3 Tablets)","description":"\u003cp\u003eMigraine symptoms may be caused by swollen blood vessels in the head. It is thought to reduce the widening of these blood vessels. This helps to take away the headache and other symptoms of a migraine attack, such as feeling of being sick (nausea or vomiting) and being sensitive to light and sound.\u003c\/p\u003e","brand":"Valor Pharma","offers":[{"title":"Default Title","offer_id":47654691897574,"sku":null,"price":290.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/triptan.png?v=1781940249"},{"product_id":"mosegor-tablets-0-5mg-1-strip-10-tablets","title":"Mosegor Tablets 0.5mg (1 Strip = 10 Tablets)","description":"\u003cp\u003ePizotifen is a tricyclic (Benzocycloheptathiophene) compound possessing structural similarities to cyproheptadine and the tricyclic antidepressant drugs. Pharmacodynamic studies demonstrate pizotifen to have powerful antiserotonin and antitryptaminic properties and marked antihistaminic effects. It also possesses weak anticholinergic effects and sedative properties.The prophylactic effect of pizotifen in migraine is associated with its ability to modify the humoral mechanisms of headache. It inhibits the permeability increasing effect of serotonin and histamine on the affected cranial vessels, thereby checking the transudation of plasmakinin so that the pain threshold of the receptors is maintained at 'normal' levels. In the sequence of events leading to the migraine attack, depletion of plasma serotonin contributes to loss of tone in the extracranial vessels. Pizotifen inhibits serotonin re-uptake by the platelets, thus maintaining plasma serotonin and preventing the loss of tone and passive distension of the extracranial arteries.\u003c\/p\u003e","brand":"Novartis Pharmaceuticals","offers":[{"title":"Default Title","offer_id":47654691963110,"sku":null,"price":205.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/mosegor.png?v=1781940017"},{"product_id":"anex-m-tablets-85-500mg-2s","title":"Anex M Tablets 85 500mg 2s","description":"\u003cp\u003e\u003cb\u003eProduct Overview\u003c\/b\u003e\u003cbr\u003e\u003cspan\u003eAnex M Tablets 85 500mg 2s is a medication manufactured by Pharmevo (Pvt) Ltd that contains a combination of Naproxen and Sumatriptan. These tablets are commonly used for the treatment of migraines and severe headaches.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eKey Benefits\u003c\/b\u003e\u003cbr\u003e\u003cspan\u003e- Provides fast relief from migraines and severe headaches\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e- Combines two powerful ingredients for maximum effectiveness\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e- Reduces inflammation and pain associated with migraines\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e- Easy-to-take tablet form for convenience\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eHow It Works\u003c\/b\u003e\u003cbr\u003e\u003cspan\u003eNaproxen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. Sumatriptan is a serotonin receptor agonist that works by narrowing blood vessels in the brain to reduce headache pain. Together, these ingredients provide fast and effective relief from migraines.\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Pharmevo Private Limited.","offers":[{"title":"Default Title","offer_id":47905072840934,"sku":null,"price":391.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/anexm.png?v=1781940391"}],"url":"https:\/\/www.glitzson.com\/collections\/migraine.oembed","provider":"Glitzson","version":"1.0","type":"link"}