{"product_id":"domel-suspension-60ml","title":"Domel Suspension 60ml","description":"\u003cp\u003eDomel Suspension 60ml Specification\u003cbr\u003e\nRequires Prescription (YES\/NO)\u003cbr\u003e\nYes\u003c\/p\u003e\n\n\u003cp\u003eGenerics\u003cbr\u003e\nDomeperidone Maleate\u003c\/p\u003e\n\n\u003cp\u003eUsed For\u003cbr\u003e\nNausea \u0026amp; Vomiting\u003c\/p\u003e\n\n\u003cp\u003eHow it works\u003cbr\u003e\nIts anti emetic effect may be due to a combination of peripheral (gastrokinetic) effects and antagonism of dopamine receptors in the chemoreceptor trigger zone, which lies outside the blood brain barrier in the area postrema.\u003c\/p\u003e\n\n\u003cp\u003eUsage And Safety\u003cbr\u003e\nDosage\u003cbr\u003e\nAdults : 10-20mg orally 3-4 times daily before meals , max 80mg daily. Re-evaluate need for continued treatment after 4 week. Children : Nausea \u0026amp; Vomiting - 0.25-0.5mg\/kg body-wt , 3-4 times daily, max 2.4mg\/kg daily. OR As directed by your physician.\u003c\/p\u003e\n\n\u003cp\u003eSide Effects\u003cbr\u003e\nDepression (2.5%) Anxiety (1.6%) Libido Decreased\/Loss of Libido , Headache (5.6%) , Somnolence (2.5%) , Akathisia (1%) , Diarrhea (5.2%) , Rash (2.8%), Pruritus (1.7%) , Breast Enlargement \/ Gynaecomastia (5.3%) Breast Tenderness (4.4%), Galactorrhoea (3.3%) , Amenorrhea (2.9%) , Breast Pain (2.3%), , Menstruation Irregular (2.0%) , Lactation Disorder (1.6%).\u003c\/p\u003e\n\n\u003cp\u003eDrug Interactions\u003cbr\u003e\nCYP3A4 inhibitors such as indinavir , Anti arrhythmics class IA (e.g., disopyramide, quinidine), anti arrhythmics class III (e.g., amiodarone, dofetilide, dronedarone, ibutilide, sotalol), certain antipsychotics (e.g., haloperidol, pimozide, sertindole), certain antidepressants (e.g., citalopram, escitalopram), certain antibiotics (e.g., levofloxacin, moxifloxacin), certain antifungal agents (e.g., pentamidine), certain antimalarial agents (e.g., halofantrine), certain gastro intestinal drugs (e.g., dolasetron), certain drugs used in cancer (e.g., toremifene, vandetanib), certain other drugs (e.g., bepridil, methadone).\u003c\/p\u003e\n\n\u003cp\u003eIndication\u003cbr\u003e\nIt is used in the treatment of nausea and vomiting.\u003c\/p\u003e\n\n\u003cp\u003eWhen not to Use\u003cbr\u003e\nDomeperidone is contraindicated in the following situations: • In patients with moderate to severe hepatic impairment • In patients who have known existing prolongation of cardiac conduction intervals (particularly QTc) and in patients with significant electrolyte disturbances or underlying cardiac diseases such as congestive heart failure.\u003c\/p\u003e\n\n\u003cp\u003ePrecautions\u003cbr\u003e\nPrecaution\u003cbr\u003e\nEpidemiological studies have shown domperidone may be associated with an increased risk of serious ventricular arrhythmias or sudden cardiac death.\u003c\/p\u003e\n\n\u003cp\u003eWarnings\u003cbr\u003e\nWarning 1\u003cbr\u003e\nPatients older than 60 years of age should consult their physician before taking domeperidone maleate.\u003c\/p\u003e\n\n\u003cp\u003eWarning 2\u003cbr\u003e\nDue to increased risk of ventricular arrhythmia, domeperidone maleate is not recommended in patients with known existing prolongation of cardiac conduction intervals, particularly QTc, in patients with significant electrolyte disturbances.\u003c\/p\u003e\n\n\u003cp\u003eWarning 3\u003cbr\u003e\nTreatment with domeperidone maleate should be stopped if signs or symptoms occur that may be associated with cardiac arrhythmia, and the patient should promptly consult their physician.\u003c\/p\u003e\n\n\u003cp\u003eAdditional Information\u003cbr\u003e\nPregnancy category\u003cbr\u003e\nAlways consult your physician before using any medicine.\u003c\/p\u003e\n\n\u003cp\u003eStorage (YES\/NO)\u003cbr\u003e\nStore this medicine at room temperature, away from direct light and heat.\u003c\/p\u003e","brand":"Barrett Hodgson Pakistan","offers":[{"title":"Default Title","offer_id":47654564856038,"sku":null,"price":100.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/DomelSuspension60ml.png?v=1781333447","url":"https:\/\/www.glitzson.com\/products\/domel-suspension-60ml","provider":"Glitzson","version":"1.0","type":"link"}