{"product_id":"esobrain-40mg-capsule-14-cap-in-box","title":"ESOBRAIN 40MG CAPSULE (14 CAP IN BOX)","description":"\u003cp\u003e\u003cspan\u003eGenerics\u003cbr\u003eEsomeprazole\u003cbr\u003e\u003cbr\u003eUsed For\u003cbr\u003eAcidity \u0026amp; Ulcers\u003cbr\u003e\u003cbr\u003eHow it works\u003cbr\u003eEsomeprazole works by binding irreversibly to the H+\/K+ ATPase in the proton pump. Because the proton pump is the final pathway for secretion of hydrochloric acid by the parietal cells in the stomach, its inhibition dramatically decreases the secretion of hydrochloric acid into the stomach and alters gastric pH .\u003cbr\u003e\u003cbr\u003eUsage And Safety\u003cbr\u003eDosage\u003cbr\u003eAdults : GERD : For Adults : 20mg or 40mg once daily for 4 to 8 weeks. 12 to 17 years -- 20mg or 40mg once dailly for upto 8 weeks. Gastric Ulcers : 20mg or 40mg once daily for upto 6 months . Erosive oesophagitis : 40mg once daily for 4-8 wk . Prevention of relapse , 20mg once daily . Children : Not recommended . OR As directed by your physician .\u003cbr\u003e\u003cbr\u003eSide Effects\u003cbr\u003eHeadache , GI upset , Skin reactions , Dry mouth. Rarely angioedema . Rarely angiooedema , anaphylaxis , fundic gland polyps.\u003cbr\u003e\u003cbr\u003eDrug Interactions\u003cbr\u003ePhenytoin , warfarin , clopidogrel , ketoconazole , itraconazole , voriconazole , diazepam , citalopram , imipramine , clomipramine , CYP3A4 inhibitors or inducers , tacrolimus , digoxin , erlitinib , methotraxate\u003cbr\u003e\u003cbr\u003eIndication\u003cbr\u003eTreatment of Heartburn , GERD , Gastritis \u0026amp; Ulcer\u003cbr\u003e\u003cbr\u003eWhen not to Use\u003cbr\u003eIt is contraindicated in patients with known hypersensitivity to proton pump inhibitors (PPIs). Hypersensitivity reactions e.g. angioedema and anaphylaxis, bronchospasm, acute interstitial nephritis and urticaria have been reported with esomeprazole use.\u003cbr\u003e\u003cbr\u003ePrecautions\u003cbr\u003ePrecaution\u003cbr\u003eDaily long-term use (e.g. longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.\u003cbr\u003e\u003cbr\u003eWarnings\u003cbr\u003eWarning 1\u003cbr\u003eHypomagnesemia has been reported rarely with prolonged treatment with PPIs.\u003cbr\u003e\u003cbr\u003eWarning 2\u003cbr\u003eLong-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine.\u003cbr\u003e\u003cbr\u003eWarning 3\u003cbr\u003eAvoid concomitant use of Esomeprazole with clopidogrel.\u003cbr\u003e\u003cbr\u003eAdditional Information\u003cbr\u003ePregnancy category\u003cbr\u003eAlways consult your physician before using any medicine.\u003cbr\u003e\u003cbr\u003eStorage (YES\/NO)\u003cbr\u003eStore this medicine at room temperature, away from direct light and heat.\u003c\/span\u003e\u003c\/p\u003e","brand":"SHAWAN PHARMACEUTICALS","offers":[{"title":"Default Title","offer_id":47900936995046,"sku":null,"price":550.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/ESOBRAIN40MG.png?v=1781786504","url":"https:\/\/www.glitzson.com\/products\/esobrain-40mg-capsule-14-cap-in-box","provider":"Glitzson","version":"1.0","type":"link"}