{"product_id":"gravinate-60ml-liquid-12-5mg-4ml","title":"Gravinate 60ml Liquid 12.5mg\/4ml","description":"\u003cp\u003eGravinate 60ml Liquid 12.5mg\/4ml Specification\u003cbr\u003e\nRequires Prescription (YES\/NO)\u003cbr\u003e\nNo\u003c\/p\u003e\n\n\u003cp\u003eGenerics\u003cbr\u003e\nDimenhydrinate\u003c\/p\u003e\n\n\u003cp\u003eUsed For\u003cbr\u003e\nVomiting Relief\u003c\/p\u003e\n\n\u003cp\u003eHow it works\u003cbr\u003e\nThe mechanism by which dimenhydrinate exerts its antiemetic, anti-motion sickness, and antivertigo effects is not precisely known, but may possibly be related to its central anticholinergic action. Other actions may involve an effect on the medullary chemoreceptor trigger zone or dose-related inhibition of vestibular stimulation (i.e., first acting on the otolith system and in larger doses on the semicircular canals).\u003c\/p\u003e\n\n\u003cp\u003eUsage And Safety\u003cbr\u003e\nDosage\u003cbr\u003e\nAdults : 50-100mg two or three times daily. Children : Under 1 yr, Not recommended; 1-6yr, 12.5mg\/kg or 37.5mg\/square meter 4 times daily, max 300mg\/day. OR As directed by your physician.\u003c\/p\u003e\n\n\u003cp\u003eSide Effects\u003cbr\u003e\nHeadache , Dry mouth , Difficulty urinating , Drowsiness, feeling less alert, somnolence (mainly observed in early treatment), Vertigo , Myasthenia (a disease which causes weak muscles) , Increased intraocular pressure , Balance problems, memory or concentration difficulties (more frequent in the elderly) , Confusion, hallucinations (seeing or hearing things that aren’t really there) , Difficulty sleeping , Difficulty moving, involuntary muscle movements .\u003c\/p\u003e\n\n\u003cp\u003eDrug Interactions\u003cbr\u003e\nCNS depressants (e.g. tranquillizers, hypnotics and anxiolytics), Monoamine oxidase inhibitors (MAOIs) , anticholinergic drugs (e.g. atropine, tricyclic antidepressants) , CYP2D6, such as metoprolol and venlafaxine.\u003c\/p\u003e\n\n\u003cp\u003eIndication\u003cbr\u003e\nIt is indicated for use in the prevention and relief of nausea, vomiting and\/or vertigo .\u003c\/p\u003e\n\n\u003cp\u003eWhen not to Use\u003cbr\u003e\nPatients who are hypersensitive to dimenhydrinate or its components (diphenhydramine or 8-chlorotheophylline) or to any ingredient in the formulations or component of the container. - During or within two weeks following therapy with a monoamine oxidase inhibitor . - Patients with glaucoma (narrow angle) ? Patients with chronic lung disease .\u003c\/p\u003e\n\n\u003cp\u003ePrecautions\u003cbr\u003e\nPrecaution\u003cbr\u003e\nDiphenhydramine should be used with caution in patients with myasthenia gravis, epilepsy or seizure disorders, prostatic hypertrophy, urinary retention, narrow-angle glaucoma, asthma, bronchitis and chronic obstructive pulmonary disease (COPD), moderate to severe hepatic impairment and moderate to severe renal impairment.\u003c\/p\u003e\n\n\u003cp\u003eWarnings\u003cbr\u003e\nWarning 1\u003cbr\u003e\nTolerance may develop with continuous use. Seek medical advice if sleeplessness persists, as insomnia may be a symptom of a serious underlying medical illness.\u003c\/p\u003e\n\n\u003cp\u003eWarning 2\u003cbr\u003e\nAvoid use of other antihistamine-containing preparations, including topical antihistamines and cough and cold medicines.\u003c\/p\u003e\n\n\u003cp\u003eWarning 3\u003cbr\u003e\nUse with caution in the elderly, who are more likely to experience side-effects.\u003c\/p\u003e\n\n\u003cp\u003eAdditional Information\u003cbr\u003e\nPregnancy category\u003cbr\u003e\nAlways consult your physician before using any medicine.\u003c\/p\u003e","brand":"Searle Pakistan (Pvt) Ltd.","offers":[{"title":"Default Title","offer_id":47654564790502,"sku":null,"price":109.66,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/Gravinate60mlLiquid.png?v=1781505098","url":"https:\/\/www.glitzson.com\/products\/gravinate-60ml-liquid-12-5mg-4ml","provider":"Glitzson","version":"1.0","type":"link"}