{"product_id":"nexum-iv-injection-40mg-1-box-1-injection","title":"Nexum Iv Injection 40mg (1 Box = 1 Injection)","description":"\u003cp\u003eNexum Iv Injection 40mg (1 Box = 1 Injection) Specification\u003cbr\u003e\nRequires Prescription (YES\/NO)\u003cbr\u003e\nYes\u003c\/p\u003e\n\n\u003cp\u003eGenerics\u003cbr\u003e\nEsomeprazole\u003c\/p\u003e\n\n\u003cp\u003eUsed For\u003cbr\u003e\nAcidity \u0026amp; Ulcers\u003c\/p\u003e\n\n\u003cp\u003eHow it works\u003cbr\u003e\nEsomeprazole works by binding irreversibly to the H+\/K+ ATPase in the proton pump. Because the proton pump is the final pathway for secretion of hydrochloric acid by the parietal cells in the stomach, its inhibition dramatically decreases the secretion of hydrochloric acid into the stomach and alters gastric pH .\u003c\/p\u003e\n\n\u003cp\u003eUsage And Safety\u003cbr\u003e\nDosage\u003cbr\u003e\nAdults : 40mg once daily given as IV inj over a period of atleast 3 min or as IV inf over a period of 10-30mins. Children : By IV injection or by IV infusion . GERD in the presence of erosive reflux oesophagitis : 1-12 yr , body weight under 20kg , 10mg once daily ; body weight over 20 kg , 10-20mg once daily ; 12-18 yr , 40mg obce daily . GERD in the absence of erosive reflux oesophagitis : 1-12yr, 10mg once daily ; 12-18yr , 20mg once daily . OR As directed by your physician.\u003c\/p\u003e\n\n\u003cp\u003eSide Effects\u003cbr\u003e\nHeadache , GI upset , Skin reactions , Dry mouth. Rarely angioedema . Rarely angiooedema , anaphylaxis , fundic gland polyps.\u003c\/p\u003e\n\n\u003cp\u003eDrug Interactions\u003cbr\u003e\nPhenytoin , warfarin , clopidogrel , ketoconazole , itraconazole , voriconazole , diazepam , citalopram , imipramine , clomipramine , CYP3A4 inhibitors or inducers , tacrolimus , digoxin , erlitinib , methotraxate\u003c\/p\u003e\n\n\u003cp\u003eIndication\u003cbr\u003e\nTreatment of Heartburn , GERD , Gastritis \u0026amp; Ulcer\u003c\/p\u003e\n\n\u003cp\u003eWhen not to Use\u003cbr\u003e\nIt is contraindicated in patients with known hypersensitivity to proton pump inhibitors (PPIs). Hypersensitivity reactions e.g. angioedema and anaphylaxis, bronchospasm, acute interstitial nephritis and urticaria have been reported with esomeprazole use.\u003c\/p\u003e\n\n\u003cp\u003ePrecautions\u003cbr\u003e\nPrecaution\u003cbr\u003e\nDaily long-term use (e.g. longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.\u003c\/p\u003e\n\n\u003cp\u003eWarnings\u003cbr\u003e\nWarning 1\u003cbr\u003e\nHypomagnesemia has been reported rarely with prolonged treatment with PPIs.\u003c\/p\u003e","brand":"Getz Pharma Pakistan","offers":[{"title":"Default Title","offer_id":47654560760038,"sku":null,"price":650.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/NexumIvInjection40mg.png?v=1781587647","url":"https:\/\/www.glitzson.com\/products\/nexum-iv-injection-40mg-1-box-1-injection","provider":"Glitzson","version":"1.0","type":"link"}