{"product_id":"oratane-softgel-capsules-20mg-1-box-3-strips-1-strip-10-capsules","title":"Oratane Softgel Capsules 20mg (1 Box = 3 Strips) (1 Strip = 10 Capsules)","description":"\u003cp\u003eOratane Softgel Capsules 20mg\u003c\/p\u003e\n\n\u003cp\u003ePack Size: 1 Box (3 Strips × 10 Softgel Capsules)\u003cbr\u003e\nGeneric Name: Isotretinoin\u003cbr\u003e\nDosage Form: Oral Softgel Capsules\u003cbr\u003e\nTherapeutic Category: Oral Retinoid \/ Systemic Acne Treatment\u003cbr\u003e\nPrescription Required: Yes\u003c\/p\u003e\n\n\u003cp\u003eOratane 20mg (Isotretinoin) – Oral Treatment for Severe Acne\u003c\/p\u003e\n\n\u003cp\u003eOratane Softgel Capsules 20mg contain Isotretinoin, a potent oral retinoid derived from Vitamin A. It is prescribed for the treatment of severe acne vulgaris, including nodular acne, cystic acne, conglobate acne, and acne at risk of permanent scarring, particularly in adults and adolescents who have not responded to conventional acne therapies such as topical treatments or oral antibiotics.\u003c\/p\u003e\n\n\u003cp\u003eThis systemic acne medication is considered one of the most effective treatments for persistent, treatment-resistant acne.\u003c\/p\u003e\n\n\u003cp\u003eHow Oratane (Isotretinoin) Works\u003c\/p\u003e\n\n\u003cp\u003eIsotretinoin is a stereoisomer of all-trans retinoic acid (tretinoin). Although its exact mechanism is not fully understood, clinical studies show that it works by:\u003c\/p\u003e\n\n\u003cp\u003eSuppressing sebaceous gland activity\u003c\/p\u003e\n\n\u003cp\u003eReducing the size of sebaceous (oil) glands\u003c\/p\u003e\n\n\u003cp\u003eDecreasing excess sebum production\u003c\/p\u003e\n\n\u003cp\u003ePreventing clogged pores\u003c\/p\u003e\n\n\u003cp\u003eReducing inflammation in the skin\u003c\/p\u003e\n\n\u003cp\u003eBy targeting the root causes of acne — excess oil, inflammation, and abnormal skin cell turnover — isotretinoin significantly improves severe acne and reduces the risk of acne scarring.\u003c\/p\u003e\n\n\u003cp\u003eIndications\u003c\/p\u003e\n\n\u003cp\u003eOratane 20mg is indicated for:\u003c\/p\u003e\n\n\u003cp\u003eSevere nodular acne\u003c\/p\u003e\n\n\u003cp\u003eCystic acne\u003c\/p\u003e\n\n\u003cp\u003eConglobate acne\u003c\/p\u003e\n\n\u003cp\u003eAcne resistant to antibiotics or topical therapy\u003c\/p\u003e\n\n\u003cp\u003eAcne with high risk of permanent scarring\u003c\/p\u003e\n\n\u003cp\u003eDosage \u0026amp; Administration\u003c\/p\u003e\n\n\u003cp\u003eAdults and Adolescents:\u003c\/p\u003e\n\n\u003cp\u003eInitial dose: 0.5 mg\/kg body weight daily, taken with food (as a single dose or divided doses) for 4 weeks.\u003c\/p\u003e\n\n\u003cp\u003eMaintenance dose: Adjusted between 0.1–1 mg\/kg\/day based on response for an additional 8–12 weeks.\u003c\/p\u003e\n\n\u003cp\u003eMaximum cumulative dose: 150 mg\/kg per course.\u003c\/p\u003e\n\n\u003cp\u003eRepeat courses are generally not recommended.\u003c\/p\u003e\n\n\u003cp\u003eChildren: Not recommended.\u003c\/p\u003e\n\n\u003cp\u003eAlways follow your dermatologist’s instructions carefully.\u003c\/p\u003e\n\n\u003cp\u003eCommon Side Effects\u003cbr\u003e\nCommon (Up to 1 in 10 people)\u003c\/p\u003e\n\n\u003cp\u003eHeadache\u003c\/p\u003e\n\n\u003cp\u003eDry lips and skin (very common with isotretinoin therapy)\u003c\/p\u003e\n\n\u003cp\u003eIncreased cholesterol or triglycerides\u003c\/p\u003e\n\n\u003cp\u003eProtein or blood in urine\u003c\/p\u003e\n\n\u003cp\u003eNasal dryness and mild nosebleeds\u003c\/p\u003e\n\n\u003cp\u003eSore throat or inflamed nasal passages\u003c\/p\u003e\n\n\u003cp\u003eIncreased susceptibility to infections\u003c\/p\u003e\n\n\u003cp\u003eAllergic reactions (rash, itching)\u003c\/p\u003e\n\n\u003cp\u003eRare\u003c\/p\u003e\n\n\u003cp\u003eTemporary hair loss (alopecia)\u003c\/p\u003e\n\n\u003cp\u003eVery Rare\u003c\/p\u003e\n\n\u003cp\u003eNight vision problems\u003c\/p\u003e\n\n\u003cp\u003eIncreased sensitivity to light (photosensitivity)\u003c\/p\u003e\n\n\u003cp\u003eBlurred or distorted vision\u003c\/p\u003e\n\n\u003cp\u003eCorneal opacity or cataracts\u003c\/p\u003e\n\n\u003cp\u003eSeek medical attention if you experience severe allergic reactions or vision changes.\u003c\/p\u003e\n\n\u003cp\u003eDrug Interactions\u003c\/p\u003e\n\n\u003cp\u003eDo NOT take Oratane with:\u003c\/p\u003e\n\n\u003cp\u003eVitamin A supplements (risk of toxicity)\u003c\/p\u003e\n\n\u003cp\u003eTetracycline antibiotics\u003c\/p\u003e\n\n\u003cp\u003eOther systemic retinoids\u003c\/p\u003e\n\n\u003cp\u003eTopical keratolytic or exfoliating anti-acne treatments\u003c\/p\u003e\n\n\u003cp\u003eMoisturizers and emollients are safe and recommended to manage dryness.\u003c\/p\u003e\n\n\u003cp\u003eWhen Not to Use\u003c\/p\u003e\n\n\u003cp\u003eDo NOT take Isotretinoin if:\u003c\/p\u003e\n\n\u003cp\u003eYou are pregnant or breastfeeding\u003c\/p\u003e\n\n\u003cp\u003eYou may become pregnant (strict pregnancy prevention required)\u003c\/p\u003e\n\n\u003cp\u003eYou are allergic to isotretinoin, peanuts, soya, or any ingredients\u003c\/p\u003e\n\n\u003cp\u003eYou have liver disease\u003c\/p\u003e\n\n\u003cp\u003eYou have very high cholesterol or triglyceride levels\u003c\/p\u003e\n\n\u003cp\u003eImportant Warnings \u0026amp; Precautions\u003cbr\u003e\nPregnancy Warning (Teratogenic Risk)\u003c\/p\u003e\n\n\u003cp\u003eIsotretinoin can cause severe birth defects.\u003c\/p\u003e\n\n\u003cp\u003eStrict contraception is required during treatment and for at least 1 month after stopping therapy.\u003c\/p\u003e\n\n\u003cp\u003eDo not donate blood during treatment and for 1 month after stopping.\u003c\/p\u003e\n\n\u003cp\u003eMental Health Monitoring\u003c\/p\u003e\n\n\u003cp\u003eInform your doctor if you have a history of:\u003c\/p\u003e\n\n\u003cp\u003eDepression\u003c\/p\u003e\n\n\u003cp\u003eMood disorders\u003c\/p\u003e\n\n\u003cp\u003eAggressive behavior\u003c\/p\u003e\n\n\u003cp\u003eSuicidal thoughts\u003c\/p\u003e\n\n\u003cp\u003eMood changes have been reported during isotretinoin treatment.\u003c\/p\u003e\n\n\u003cp\u003eLiver \u0026amp; Blood Monitoring\u003c\/p\u003e\n\n\u003cp\u003eRegular blood tests are required to monitor:\u003c\/p\u003e\n\n\u003cp\u003eLiver function (liver enzymes)\u003c\/p\u003e\n\n\u003cp\u003eCholesterol and triglycerides\u003c\/p\u003e\n\n\u003cp\u003eOverall treatment safety\u003c\/p\u003e\n\n\u003cp\u003eYour dose may be adjusted if abnormalities occur.\u003c\/p\u003e\n\n\u003cp\u003eSpecialist Supervision\u003c\/p\u003e\n\n\u003cp\u003eIsotretinoin should only be prescribed and monitored by a dermatologist or physician experienced in systemic retinoid therapy.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions\u003c\/p\u003e\n\n\u003cp\u003eStore at room temperature\u003c\/p\u003e\n\n\u003cp\u003eProtect from direct light and heat\u003c\/p\u003e\n\n\u003cp\u003eKeep out of reach of children\u003c\/p\u003e","brand":"Crystolite Pharmaceuticals","offers":[{"title":"Default Title","offer_id":47654547620070,"sku":null,"price":2995.1,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/OrataneSoftgelCapsules20mg.png?v=1781086989","url":"https:\/\/www.glitzson.com\/products\/oratane-softgel-capsules-20mg-1-box-3-strips-1-strip-10-capsules","provider":"Glitzson","version":"1.0","type":"link"}