{"product_id":"raay-20mg-tab-7tab-1-strip-2-strip-14-tab","title":"RAAY 20MG TAB (7TAB =1 STRIP 2 STRIP =14 TAB)","description":"\u003cp\u003e\u003cspan\u003eRAAYTablets 20mg (1 Box = 1 Strip)(1 Strip = 14 Tablets) Specification\u003cbr\u003eRequires Prescription (YES\/NO)\u003cbr\u003eYes\u003cbr\u003e\u003cbr\u003eUsed For\u003cbr\u003eDepression\u003cbr\u003e\u003cbr\u003eHow it works\u003cbr\u003eThe mechanism of action of citalopram HBr as an antidepressant is presumed to be linked to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT). In vitro and in vivo studies in animals suggest that citalopram is a highly selective serotonin reuptake inhibitor (SSRI) with minimal effects on norepinephrine (NE) and dopamine (DA) neuronal reuptake. Tolerance to the inhibition of 5-HT uptake is not induced by long-term (14-day) treatment of rats with citalopram. Citalopram is a racemic mixture (50\/50), and the inhibition of 5-HT reuptake by citalopram is primarily due to the (S)-enantiomer.\u003cbr\u003e\u003cbr\u003eUsage And Safety\u003cbr\u003eDosage\u003cbr\u003eAdults : Initially 20mg daily as a single dose , increasing if necessary to max 60mg daily according to response . Elderly : Initially 20mg daily as a single dose , increasing if necessary to max 40mg daily according to response. Children : Not recommended. OR As directed by your physician .\u003cbr\u003e\u003cbr\u003eSide Effects\u003cbr\u003eGI upset , tremor , somnolence , dry mouth , anorexia , agitation , decreased lipid , anxiety , confusion , sleep disorders , tinnitus , yawning , pruritis , impotence , amnesia , apathy , increases salivation , increased sweating , abnormal accommodation. Hyponatraemia , bleeding disorders , serotonin syndrome .\u003cbr\u003e\u003cbr\u003eDrug Interactions\u003cbr\u003eMAOIs, lithium , tryptophan , pimozide , other neuroleptics , St.John's wort, other SSRIs , SNRIs , 5HT1 agonists , triptans , other serotonergic drugs , linezolid , drugs that prolong QT interval , tramadol , anticoagulants , NSAIDs and other drugs affecting plastelet function . CYP2D6 substrates (e.g., metoprolol) , CYP2C19 inhibitors (e.g. PPIs) , cimetidine , drugs that reduce seizure threshold . Drugs that induce hypokalaemia or hypomagnesaemia. Alcohol.\u003cbr\u003e\u003cbr\u003eIndication\u003cbr\u003eIt is used in depressive disorders (endogenous and non-endogenous).\u003cbr\u003e\u003cbr\u003eWhen not to Use\u003cbr\u003eHyersensitive to any of the ingredients.\u003cbr\u003e\u003cbr\u003ePrecautions\u003cbr\u003ePrecaution\u003cbr\u003eAll patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases.\u003cbr\u003e\u003cbr\u003eWarnings\u003cbr\u003eWarning 1\u003cbr\u003eAntidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of this medicine or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need.\u003cbr\u003e\u003cbr\u003eWarning 2\u003cbr\u003ePatients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior.\u003cbr\u003e\u003cbr\u003eWarning 3\u003cbr\u003eFamilies and caregivers should be advised of the need for close observation and communication with the prescriber. It is not approved for use in pediatric patients.\u003cbr\u003e\u003cbr\u003eAdditional Information\u003cbr\u003ePregnancy category\u003cbr\u003eAlways consult your physician before using any medicine.\u003cbr\u003e\u003cbr\u003eStorage (YES\/NO)\u003cbr\u003eStore this medicine at room temperature, away from direct light and heat.\u003c\/span\u003e\u003c\/p\u003e","brand":"SHAWAN PHARMACEUTICALS","offers":[{"title":"Default Title","offer_id":47900910256358,"sku":null,"price":500.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/RAAY20MGTAB.png?v=1781783884","url":"https:\/\/www.glitzson.com\/products\/raay-20mg-tab-7tab-1-strip-2-strip-14-tab","provider":"Glitzson","version":"1.0","type":"link"}