{"product_id":"risek-insta-sugar-free-sachets-40mg-1-box-10-sachets","title":"Risek Insta Sugar Free Sachets 40mg (1 Box = 10 Sachets)","description":"\u003cp\u003eRisek Insta Sugar Free Sachets 40mg (1 Box = 10 Sachets) Specification\u003cbr\u003e\nRequires Prescription (YES\/NO)\u003cbr\u003e\nYes\u003c\/p\u003e\n\n\u003cp\u003eGenerics\u003cbr\u003e\nOmeprazole + Sodium Bicarbonte\u003c\/p\u003e\n\n\u003cp\u003eUsed For\u003cbr\u003e\nGastroesophageal Reflux Disease\u003c\/p\u003e\n\n\u003cp\u003eHow it works\u003cbr\u003e\nOmeprazole reduces gastric acid secretion through a unique mechanism of action. Omeprazole belongs to a class of anti-secretory compounds - the substituted benzimidazoles that do not exhibit anti-cholinergic or H2 histamine antagonistic properties. It inhibits secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen\/potassium adenosine triphosphatase (H+\/K+ATPase), the proton pump of the gastric parietal cell. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.\u003c\/p\u003e\n\n\u003cp\u003eUsage And Safety\u003cbr\u003e\nDosage\u003cbr\u003e\nShort term treatment of active duodenal ulcer : 20mg Once daily for 4 weeks. For Benign gastric ulcer : 40mg Once daily for 4-8 weeks ; Reduction of risk of upper gastrointestinal bleeding in critically ill patients (40mg oral suspension only) : 40mg initially follwed by 40mg 6-8 hours later and 40mg daily thereafter for 14 days . Gastroesophageal Reflux Disease (GERD) : Symptomatic GERD (with no esophageal erosions) : 20mg Once daily for up to 4 weeks , Erosive esophagitis : 20mg Once daily for 4-8 weeks ; Maintenance of healing of erosive esophagitis : 20mg Once daily OR As directed by your physician.\u003c\/p\u003e\n\n\u003cp\u003eSide Effects\u003cbr\u003e\nCommon : Central and peripheral nervous system: Headache. Gastrointestinal: Diarrhea, constipation, abdominal pain, nausea\/vomiting and flatulence.Uncommon : Central and peripheral nervous system: Dizziness, paraesthesia, somnolence, insomnia and vertigo.Hepatic: Increased liver enzymesSkin: Rash and\/or pruritis, urticariaOther: MalaiseRare : Central and peripheral nervous system: Reversible mental confusion, agitation,aggression, depression and hallucinations, predominantly in severely ill patients.Endocrine: Gynecomastia\u003c\/p\u003e\n\n\u003cp\u003eDrug Interactions\u003cbr\u003e\nKetoconazole and itraconazole , diazepam, citalopram, imipramine, clomipramine, phenytoin , Atazanavir , Digoxin , Clopidogrel , posaconazole, erlotinib , Saquinavir , Tacrolimus , Methotrexate , clarithromycin , CYP2C19 or CYP3A4 or both (such as rifampicin and St John's wort.\u003c\/p\u003e\n\n\u003cp\u003eIndication\u003cbr\u003e\nIt (Omeprazole) is indicated in adults for the treatment of: Gastro-Esophageal Reflux Disease (GERD):- Treatment of erosive reflux esophagitis.- Long term management of patients with healed esophagitis to prevent relapse.- Symptomatic treatment of gastroesophageal reflux disease (GERD).\u003c\/p\u003e\n\n\u003cp\u003eWhen not to Use\u003cbr\u003e\nOmeprazole is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles. Omeprazole must not be used concomitantly with nelfinavir.\u003c\/p\u003e\n\n\u003cp\u003ePrecautions\u003cbr\u003e\nPrecaution\u003cbr\u003e\nSymptomatic response to therapy with omeprazole does not preclude the presence of gastric malignancy .\u003c\/p\u003e\n\n\u003cp\u003eWarnings\u003cbr\u003e\nWarning 1\u003cbr\u003e\nAtrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with omeprazole .\u003c\/p\u003e\n\n\u003cp\u003eWarning 2\u003cbr\u003e\nSodium bicarbonate should be used with caution in patients with Bartter's syndrome, hypokalemia, respiratory alkalosis, and problems with acid-base balance. Long- term administration of bicarbonate with calcium or milk can cause milk-alkali syndrome .\u003c\/p\u003e\n\n\u003cp\u003eWarning 3\u003cbr\u003e\nOmeprazole powder for oral suspension contains sodium in the form of sodium bicarbonate. This should be taken into consideration for patients on a sodium restricted diet .\u003c\/p\u003e\n\n\u003cp\u003eAdditional Information\u003cbr\u003e\nPregnancy category\u003cbr\u003e\nAlways consult your physician before using any medicine.\u003c\/p\u003e\n\n\u003cp\u003eStorage (YES\/NO)\u003cbr\u003e\nStore this medicine at room temperature, away from direct light and heat.\u003c\/p\u003e","brand":"Getz Pharma Pakistan","offers":[{"title":"Default Title","offer_id":47654564004070,"sku":null,"price":39.36,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/RisekInstaSugarFreeSachets40mg.png?v=1781677435","url":"https:\/\/www.glitzson.com\/products\/risek-insta-sugar-free-sachets-40mg-1-box-10-sachets","provider":"Glitzson","version":"1.0","type":"link"}