{"product_id":"seglutide-pen-2mg-1-box-1-prefilled-pen","title":"Seglutide Pen 2mg (1 Box = 1 Prefilled Pen)","description":"\u003cp\u003eSemaglutide is a GLP-1 analogue with 94% sequence homology to human GLP-1. Semaglutide acts as a GLP-1 receptor agonist that selectively binds to and activates the GLP-1 receptor, the target for native GLP-1. GLP-1 is a physiological hormone that has multiple actions on glucose, mediated by the GLP-1 receptors. The principal mechanism of protraction resulting in the long half-life of Semaglutide is albumin binding, which results in decreased renal clearance and protection from metabolic degradation. Furthermore, Semaglutide is stabilized against degradation by the DPP-4 enzyme. Semaglutide reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers glucagon secretion, both in a glucose-dependent manner. Thus, when blood glucose is high, insulin secretion is stimulated and glucagon secretion is inhibited. The mechanism of blood glucose lowering also involves a minor delay in gastric emptying in the early postprandial phase.\u003c\/p\u003e","brand":"Macter International","offers":[{"title":"Default Title","offer_id":47654674759910,"sku":null,"price":7600.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/SeglutidePen2mg_1Box_1PrefilledPen.png?v=1781453038","url":"https:\/\/www.glitzson.com\/products\/seglutide-pen-2mg-1-box-1-prefilled-pen","provider":"Glitzson","version":"1.0","type":"link"}