{"product_id":"vocinti-tablets-20mg-1-strip-7-tablets","title":"Vocinti Tablets 20mg (1 Strip = 7 Tablets)","description":"\u003cp\u003eVocinti Tablets 20mg (1 Strip = 7 Tablets) Specification\u003cbr\u003e\nRequires Prescription (YES\/NO)\u003cbr\u003e\nYes\u003c\/p\u003e\n\n\u003cp\u003eGenerics\u003cbr\u003e\n Vonoprazan\u003c\/p\u003e\n\n\u003cp\u003eUsed For\u003cbr\u003e\nAcidity \u0026amp; Ulcers\u003c\/p\u003e\n\n\u003cp\u003eHow it works\u003cbr\u003e\nVonoprazan is a potassium competitive acid blocker (P-CAB) and does not require activation by acid. It inhibits H+, K+-ATPase in a reversible and potassium-competitive manner. Vonoprazan has a strong basicity and resides on the acid production site of gastric parietal cells for a long time, thereby inhibiting gastric acid production. Vonoprazan exerts a strong inhibitory effect on formation of mucosal damage in upper part of the gastrointestinal tract.\u003c\/p\u003e\n\n\u003cp\u003eUsage And Safety\u003cbr\u003e\nDosage\u003cbr\u003e\nReflux esophagitis : The usual adult dose for oral use is 20mg of Vonoprazan administered once daily for a total of 4 weeks of treatment. Prevention of recurrence of gastric or duodenal ulcer during low-dose aspirin administration : The usual adult dosage is one tablet of 10mg of Vonoprazan administered orally once daily. Prevention of recurrence of gastric or duodenal ulcer during non-steroidal anti-inflammatory drug (NSAID) administration : The usual adult dosage is one tablet of 10mg of Vonoprazan administered orally once daily. Always consult your doctor or pharmacist for dose adjustments.\u003c\/p\u003e\n\n\u003cp\u003eSide Effects\u003cbr\u003e\nDiarrhea, constipation, drug hypersensitivity (including anaphylactic shock), drug eruption, urticaria, hepatotoxicity, jaundice, rash, nausea, abdominal distension, gamma-glutamyl transferase increased, AST increased, Liver function test abnormal, ALT increased, ALP increased, LDH increased, ? - GPT increased, edema and eosinophilia.\u003c\/p\u003e\n\n\u003cp\u003eDrug Interactions\u003cbr\u003e\nCYP3A4 inhibitors Clarithromycin , Digoxin, Methyldigoxin , Itraconazole, Tyrosine kinase inhibitors , Gefitinib, Nilotinib, , Erlotinib\u003c\/p\u003e\n\n\u003cp\u003eIndication\u003cbr\u003e\nVonoprazan is indicated for: Gastric ulcer, duodenal ulcer, reflux esophagitis, prevention of recurrence of gastric or duodenal ulcer during low-dose aspirin administration, prevention of recurrence of gastric or duodenal ulcer during non-steroidal anti-inflammatory drug (NSAID) administration.\u003c\/p\u003e\n\n\u003cp\u003eWhen not to Use\u003cbr\u003e\nVonoprazan is contraindicated in: • Patients with hypersensitivity to Vonoprazan or to any excipient of the product. • Patients receiving atazanavir sulphate, nelfinavir or rilpivirine hydrochloride.\u003c\/p\u003e\n\n\u003cp\u003ePrecautions\u003cbr\u003e\nPrecaution\u003cbr\u003e\nAt the treatment, the course of the disease should closely be observed and the minimum therapeutic necessity should be used according to the disease condition.\u003c\/p\u003e","brand":"Searle Pakistan (Pvt) Ltd.","offers":[{"title":"Default Title","offer_id":47654560661734,"sku":null,"price":373.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/VocintiTablets20mg.png?v=1781761571","url":"https:\/\/www.glitzson.com\/products\/vocinti-tablets-20mg-1-strip-7-tablets","provider":"Glitzson","version":"1.0","type":"link"}