{"product_id":"vonrik-tablets-20mg-1-box-2-strips-1-strip-7-tablets","title":"Vonrik Tablets 20mg (1 Box = 2 Strips) (1 Strip = 7 Tablets)","description":"\u003cp\u003eVonrik Tablets 20mg (1 Box = 2 Strips) (1 Strip = 7 Tablets) Specification\u003cbr\u003e\nRequires Prescription (YES\/NO)\u003cbr\u003e\nYes\u003c\/p\u003e\n\n\u003cp\u003eGenerics\u003cbr\u003e\n Vonoprazan\u003c\/p\u003e\n\n\u003cp\u003eUsed For\u003cbr\u003e\nAcidity \u0026amp; Ulcers\u003c\/p\u003e\n\n\u003cp\u003eHow it works\u003cbr\u003e\nVonoprazan is a potassium competitive acid blocker (P-CAB) and does not require activation by acid. It inhibits H+, K+-ATPase in a reversible and potassium-competitive manner. Vonoprazan has a strong basicity and resides on the acid production site of gastric parietal cells for a long time, thereby inhibiting gastric acid production. Vonoprazan exerts a strong inhibitory effect on formation of mucosal damage in upper part of the gastrointestinal tract.\u003c\/p\u003e\n\n\u003cp\u003eUsage And Safety\u003cbr\u003e\nDosage\u003cbr\u003e\nReflux esophagitis : The usual adult dose for oral use is 20mg of Vonoprazan administered once daily for a total of 4 weeks of treatment. Prevention of recurrence of gastric or duodenal ulcer during low-dose aspirin administration : The usual adult dosage is one tablet of 10mg of Vonoprazan administered orally once daily. Prevention of recurrence of gastric or duodenal ulcer during non-steroidal anti-inflammatory drug (NSAID) administration : The usual adult dosage is one tablet of 10mg of Vonoprazan administered orally once daily. Always consult your doctor or pharmacist for dose adjustments.\u003c\/p\u003e\n\n\u003cp\u003eSide Effects\u003cbr\u003e\nDiarrhea, constipation, drug hypersensitivity (including anaphylactic shock), drug eruption, urticaria, hepatotoxicity, jaundice, rash, nausea, abdominal distension, gamma-glutamyl transferase increased, AST increased, Liver function test abnormal, ALT increased, ALP increased, LDH increased, ? - GPT increased, edema and eosinophilia.\u003c\/p\u003e\n\n\u003cp\u003eDrug Interactions\u003cbr\u003e\nCYP3A4 inhibitors Clarithromycin , Digoxin, Methyldigoxin , Itraconazole, Tyrosine kinase inhibitors , Gefitinib, Nilotinib, , Erlotinib\u003c\/p\u003e\n\n\u003cp\u003eIndication\u003cbr\u003e\nVonoprazan is indicated for: Gastric ulcer, duodenal ulcer, reflux esophagitis, prevention of recurrence of gastric or duodenal ulcer during low-dose aspirin administration, prevention of recurrence of gastric or duodenal ulcer during non-steroidal anti-inflammatory drug (NSAID) administration.\u003c\/p\u003e\n\n\u003cp\u003eWhen not to Use\u003cbr\u003e\nVonoprazan is contraindicated in: • Patients with hypersensitivity to Vonoprazan or to any excipient of the product. • Patients receiving atazanavir sulphate, nelfinavir or rilpivirine hydrochloride.\u003c\/p\u003e\n\n\u003cp\u003ePrecautions\u003cbr\u003e\nPrecaution\u003cbr\u003e\nAt the treatment, the course of the disease should closely be observed and the minimum therapeutic necessity should be used according to the disease condition.\u003c\/p\u003e\n\n\u003cp\u003eWarnings\u003cbr\u003e\nWarning 1\u003cbr\u003e\nIn the maintenance of healing of reflux esophagitis, Vonoprazan should be administered only to the patients who repeat recurrence and recrudescence of the condition. Administration to the patients who do not necessitate maintenance of healing should be avoided.\u003c\/p\u003e\n\n\u003cp\u003eWarning 2\u003cbr\u003e\nWhen the healing is maintained over a long period and when there is no risk of recurrence, the dose reduction to a dose of 10mg from a dose 20mg, or suspension of administration should be considered.\u003c\/p\u003e\n\n\u003cp\u003eWarning 3\u003cbr\u003e\nVonoprazan should be administered with care in patients with renal disorders as a delay in the excretion of Vonoprazan may occur, which may result in an increase in the concentration of Vonoprazan in the blood.\u003c\/p\u003e\n\n\u003cp\u003eAdditional Information\u003cbr\u003e\nPregnancy category\u003cbr\u003e\nAlways consult your physician before using any medicine.\u003c\/p\u003e\n\n\u003cp\u003eStorage (YES\/NO)\u003cbr\u003e\nStore this medicine at room temperature, away from direct light and heat.\u003c\/p\u003e","brand":"High-Q International.","offers":[{"title":"Default Title","offer_id":47654558925030,"sku":null,"price":310.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0801\/6039\/1398\/files\/VonrikTablets20mg.png?v=1781762862","url":"https:\/\/www.glitzson.com\/products\/vonrik-tablets-20mg-1-box-2-strips-1-strip-7-tablets","provider":"Glitzson","version":"1.0","type":"link"}