Acdermin Gel 20g

Acdermin Gel 20g – Clindamycin & Tretinoin Gel for Acne Treatment

Prescription Required: Yes
Generic Names: Clindamycin Phosphate, Tretinoin
Dosage Form: Topical Gel
Indication: Acne Vulgaris

Product Overview

Acdermin Gel 20g is a prescription-strength combination acne treatment containing Clindamycin Phosphate, a topical antibiotic, and Tretinoin, a retinoid. It is used for the effective treatment of acne vulgaris, targeting both bacterial infection and abnormal skin cell turnover to reduce existing acne lesions and prevent new breakouts.

How Acdermin Gel Works

This dual-action formulation treats acne at multiple levels:

Clindamycin:

Inhibits the growth of Cutibacterium (Propionibacterium) acnes

Reduces inflammation caused by acne-related bacteria

Tretinoin:

Normalizes shedding of superficial skin cells

Prevents blockage of hair follicles

Reduces buildup of sebum

Helps prevent blackheads and whiteheads (early acne lesions)

Together, these actions improve skin clarity and reduce acne recurrence.

Uses and Benefits

Treatment of mild to moderate acne vulgaris

Effective against blackheads, whiteheads, pimples, and inflammatory acne

Reduces bacterial growth and inflammation

Helps unclog pores and improve skin texture

Dosage and Administration

Apply a thin layer once daily, preferably in the evening or at bedtime

Apply to clean, dry skin

Use strictly as directed by your physician or dermatologist

Possible Side Effects

Uncommon (up to 1 in 100 people):

Acne flare-up

Dry skin

Skin redness

Increased sebum production

Photosensitivity (sun sensitivity)

Itching, rash, scaly or peeling skin

Sunburn

Application-site reactions (burning, inflammation, dryness, redness)

Rare (up to 1 in 1,000 people):

Hypersensitivity reactions

Underactive thyroid symptoms (fatigue, weight gain, dry hair, cold sensitivity)

Headache

Eye irritation

Gastrointestinal symptoms (nausea, gastroenteritis)

Skin burning, irritation, pigmentation loss

Herpes simplex flare (cold sores)

Application-site swelling, discoloration, superficial skin damage

Feeling hot or pain

Consult your doctor if severe or persistent side effects occur.

Drug Interactions

Avoid or use with caution alongside:

Sulfur, salicylic acid, benzoyl peroxide, resorcinol

Erythromycin or metronidazole

Aminoglycosides

Other topical antibiotics or corticosteroids

Using these together may increase irritation or reduce effectiveness.

Indications

Indicated for topical treatment of acne vulgaris

When Not to Use Acdermin Gel

Do not use this medicine if:

You are pregnant or planning pregnancy

You are allergic to clindamycin, tretinoin, lincomycin, or any ingredient

You have Crohn’s disease, ulcerative colitis, or other chronic inflammatory bowel disease

You have a history of antibiotic-associated colitis with severe or prolonged diarrhoea

Precautions and Safety Information

For external use only

Avoid contact with eyes, mouth, mucous membranes, and broken or eczematous skin

Use caution on sensitive skin areas

Rinse immediately with lukewarm water if accidental eye contact occurs

Important Warnings

Consult your doctor before use if you have atopic eczema

Avoid sunlight and artificial UV exposure (sunlamps, tanning beds)

Use sunscreen and protective clothing when outdoors

Stop treatment and seek medical advice if acute skin inflammation develops

Pregnancy and Breastfeeding

Pregnancy Category: Always consult your physician

Contraindicated during pregnancy unless specifically prescribed

Storage Instructions

Storage Required: Yes

Store at room temperature

Protect from direct light and heat

Keep out of reach of children