Cleret Gel 20g

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Cleret Gel 20g

Generic Name: Clindamycin Phosphate + Tretinoin
Dosage Form: Topical Gel
Therapeutic Category: Anti-Acne / Dermatology Medication
Prescription Required: Yes

Cleret Gel 20g – Clindamycin & Tretinoin Gel for Acne Treatment

Cleret Gel 20g is a prescription topical acne medication that combines Clindamycin Phosphate (a topical antibiotic) and Tretinoin (a retinoid derived from Vitamin A). It is indicated for the treatment of acne vulgaris, including inflammatory acne, blackheads (comedones), whiteheads, papules, and pustules.

This dual-action acne gel works by targeting both acne-causing bacteria (Cutibacterium acnes) and abnormal skin cell turnover, helping to clear existing breakouts and prevent new acne lesions.

Active Ingredients & Mechanism of Action
Clindamycin Phosphate (Topical Antibiotic)

Inhibits the growth of acne-causing bacteria

Reduces inflammation, redness, and swelling

Helps control infected acne lesions

Tretinoin (Topical Retinoid)

Normalizes skin cell turnover

Promotes shedding of dead skin cells

Prevents clogged pores and comedone formation

Reduces excess sebum build-up

The combination therapy helps treat acne at multiple levels: bacterial control, pore unclogging, and inflammation reduction.

Indications

Cleret Gel is used for:

Mild to moderate acne vulgaris

Inflammatory acne

Blackheads and whiteheads

Oily and acne-prone skin

Dosage & Administration

Apply a thin layer once daily in the evening or at bedtime, or as directed by your physician.

Apply to clean, dry skin.

Avoid excessive application to reduce irritation.

Visible improvement may take several weeks of consistent use.

Possible Side Effects
Uncommon (Up to 1 in 100 people)

Dry skin

Redness (erythema)

Peeling or scaling

Itching or rash

Increased oil production

Photosensitivity (sun sensitivity)

Sunburn

Application site burning or irritation

Rare (Up to 1 in 1,000 people)

Hypersensitivity reactions

Headache

Eye irritation

Gastrointestinal symptoms (nausea, gastroenteritis)

Herpes simplex (cold sores)

Skin discoloration or loss of pigmentation

Underactive thyroid symptoms (rarely reported)

Application site swelling or skin damage

If severe irritation or allergic reaction occurs, discontinue use and consult your doctor.

Drug Interactions

Avoid using together with:

Sulphur-containing products

Salicylic acid

Benzoyl peroxide

Resorcinol

Erythromycin or Metronidazole

Aminoglycosides

Other topical antibiotics or corticosteroids

Combining multiple acne treatments may increase irritation or reduce effectiveness.

When Not to Use

Do NOT use Cleret Gel if:

You are pregnant or planning pregnancy (retinoids may cause birth defects)

You are allergic to Clindamycin, Tretinoin, Lincomycin, or any ingredient in the formulation

You have Crohn’s disease or ulcerative colitis

You have a history of antibiotic-associated colitis with severe diarrhea or abdominal cramps

Warnings & Precautions
External Use Only

Avoid contact with:

Eyes

Mouth

Mucous membranes

Broken, abraded, or eczematous skin

If accidental eye contact occurs, rinse thoroughly with lukewarm water.

Sun Sensitivity

Tretinoin increases photosensitivity.

Avoid sun exposure and tanning beds

Use broad-spectrum sunscreen (SPF 30 or higher)

Wear protective clothing

Atopic Eczema

Consult your doctor before use if you have chronic eczema or sensitive skin conditions.

Skin Irritation

If acute inflammation, severe redness, or excessive peeling occurs, seek medical advice.

Pregnancy & Breastfeeding

Not recommended during pregnancy.

Always consult your physician before use.

Storage Instructions

Store at room temperature

Keep away from direct sunlight and heat

Keep out of reach of children