Clobederm Ointment 0.05% 15g
Clobederm Ointment 0.05% 15g
Clobederm Ointment 0.05% 15g – Potent Topical Corticosteroid for Eczema and Skin Disorders
Clobederm Ointment 0.05% is a prescription-strength topical corticosteroid containing Clobetasol Propionate, designed to effectively manage severe inflammatory skin conditions such as eczema, psoriasis, and dermatitis. It helps reduce redness, swelling, itchiness, and irritation, offering rapid relief for chronic and relapsing skin conditions.
Prescription Requirement
Requires Prescription: Yes
Generic Name
Clobetasol Propionate – a super-potent topical corticosteroid that binds to glucocorticoid receptors in the skin, regulating gene expression to suppress inflammation and stimulate anti-inflammatory protein synthesis.
Indications / Uses
Clobederm Ointment is indicated for the treatment of:
Frequently relapsing eczema
Psoriasis (excluding widespread plaque psoriasis; for single lesions)
Lichen planus (itchy reddish-purple bumps on wrists, forearms, or legs)
Discoid lupus erythematosus (chronic scarring and photosensitive skin lesions)
Dermatitis and other steroid-resistant inflammatory skin conditions
Mechanism of Action
Clobetasol propionate binds to cytoplasmic glucocorticoid receptors, activating gene expression that produces anti-inflammatory proteins.
Inhibits the synthesis of inflammatory mediators, reducing erythema, edema, and pruritus.
Dosage & Administration
Adults: Apply a thin layer once or twice daily for up to 4 weeks, then review.
Children: Same as adults, with weekly review recommended.
Application Tips: Apply sparingly and avoid large areas or prolonged use to minimize systemic absorption.
Side Effects
Common (up to 1 in 10 users):
Burning, pain, irritation, or itching at the application site
Uncommon (up to 1 in 100 users):
Skin thinning
Stretch marks
Visible superficial blood vessels
Very Rare (up to 1 in 10,000 users):
Weight gain, moon face, obesity
Skin wrinkling, dryness, color changes
Excessive body hair or hair loss
Drug Interactions
May interact with Ritonavir and Itraconazole.
Inform your physician if you are taking other systemic or topical corticosteroids.
Precautions
Avoid applying to thin skin areas such as the face for more than 5 consecutive days.
Do not use occlusive dressings on treated areas unless directed by a physician.
Use with caution in patients using immunosuppressive medications or oral corticosteroids.
Contraindications / When Not to Use
Allergy to Clobetasol Propionate or other ingredients
Children under 1 year
Skin conditions such as:
Acne
Rosacea
Perioral dermatitis
Infected skin (unless treated concurrently)
Non-inflamed itchy skin
Widespread plaque psoriasis
Warnings
Prolonged use may increase risk of bone-related symptoms or systemic corticosteroid effects.
Avoid using under airtight dressings, including nappies, to prevent over-absorption.
Consult a physician if you notice skin infection, visual disturbances, or unusual hair growth.
Pregnancy & Lactation
Pregnancy Category: Always consult your physician before use.
Storage Instructions
Store at room temperature, away from direct sunlight, heat, and moisture.