Dermovate Ointment 20g

Dermovate Ointment 20g – Clobetasol Propionate for Severe Skin Conditions

Dermovate Ointment 20g is a prescription-only topical corticosteroid containing Clobetasol Propionate, a highly potent steroid used to treat severe inflammatory skin conditions that have not responded to milder treatments. It is commonly prescribed for eczema, psoriasis, dermatitis, and other steroid-responsive dermatoses.

Prescription Requirement

Requires Prescription: Yes

Active Ingredient (Generic Name)

Clobetasol Propionate

Therapeutic Class

Topical Corticosteroid

Super-potent steroid ointment

Uses / Indications

Dermovate Ointment is indicated for reducing redness, swelling, itching, and inflammation associated with chronic and severe skin disorders, including:

Frequently relapsing eczema

Psoriasis (excluding widespread plaque psoriasis)

Lichen planus

Discoid lupus erythematosus

Severe dermatitis

Other inflammatory skin conditions unresponsive to mild or moderate steroid creams

How Dermovate Ointment Works

Clobetasol propionate works by binding to glucocorticoid receptors in skin cells, triggering gene expression that promotes the production of anti-inflammatory proteins. At the same time, it suppresses inflammatory mediators such as prostaglandins and cytokines, resulting in rapid relief from itching, redness, and swelling.

Dosage & Administration

Adults:

Apply a thin layer once or twice daily

Maximum treatment duration: up to 4 weeks, then reassess

Children:

Same dosage as adults

Weekly medical review is required

Important:

Always use exactly as prescribed by your physician

Avoid prolonged use to reduce the risk of side effects

Possible Side Effects
Common (up to 1 in 10 people)

Burning sensation at application site

Pain, irritation, or itching

Uncommon (up to 1 in 100 people)

Skin thinning (atrophy)

Stretch marks

Increased visibility of blood vessels

Very Rare (up to 1 in 10,000 people)

Prolonged or excessive use may cause:

Weight gain

Moon face (rounded facial appearance)

Obesity

Severe skin thinning and wrinkling

Dry skin

Skin discoloration

Increased body hair or hair loss

Drug Interactions

Use with caution if taking:

Ritonavir

Itraconazole

These medicines may increase the risk of systemic corticosteroid effects.

When Not to Use Dermovate Ointment

Do not use Dermovate if:

You are allergic to clobetasol propionate or any ingredient

The patient is under 1 year of age

For the treatment of:

Acne

Rosacea

Perioral dermatitis

Genital or anal itching

Infected skin (unless combined with appropriate anti-infective treatment)

Non-inflamed itchy skin

Widespread plaque psoriasis (except isolated lesions)

Precautions

Use extreme caution on thin skin areas, especially the face

Facial use should be limited to no more than 5 days

Do not use occlusive dressings or bandages on the face

Avoid long-term continuous use

Warnings

Consult your doctor if you experience new or worsening bone pain, especially after prolonged use

Inform your healthcare provider if you are using other corticosteroids or immunosuppressive medications

Avoid use under airtight dressings or diapers, as this increases absorption and overdose risk

Pregnancy & Breastfeeding

Pregnancy Category: Consult your physician before use

Use only if clearly prescribed by a healthcare professional

Storage Instructions

Store at room temperature

Keep away from direct heat and sunlight

Keep out of reach of children