FDL Manitol 20% 500ml
FDL Manitol 20% 500ml
FDL Manitol 20% 500ml Specification
Requires Prescription (YES/NO)
Yes
Generics
Mannitol + Sorbitol
Used For
Fluids & Electrolytes
How it works
Mannitol hinders tubular reabsorption of water and enhances excretion of sodium and chloride by elevating the osmolarity of the glomerular filtrate.
Usage And Safety
Dosage
The dosage and the rate of administration depends on the fluid requirements, urinary output and the condition being treated. The usual adult dose ranges from 50-200 grams/24 hours.Reduction of intracranial pressure: In adults usually 250-300 ml. of the solution infused rapidly over 15-30 minutes.Diuresis: 50-200 grams over 24 hours in adults, preceded by a test dose of 200 mg/kg (about 60 ml. in a 50 kg. person) given over 3-5 minutes produces a diuresis of 30-50 ml/hour. Reduction of intraocular pressure: 1.5-2.0 grams/kg. (about 10-13ml/kg) over a period of 30 minutes to obtain a prompt and maximal result. The dose should be given 1-1½ hours prior to surgery to achieve maximal effect.Excretion of toxic materials: While using as an adjunctive therapy for excretion of toxic materials the dosage depends on the fluid requirements and the urine output of the patient.The recommended dose for children is 200-500 mg/kg. I.V. over 30- 60 minutes. OR As directed by your physician.
Side Effects
Chest pain, chills, thrombophlebitis and visual disturbances , Hypertension , Congestive heart failure and pulmonary edema , Hypotension due to rapid volume depletion from large diuresis , Blurred vision and convulsions may occur , Nausea and vomiting may occur , Electrolyte depletion, especially sodium , Irritation, pain and/or swelling at the injection site.
Drug Interactions
Ask your pharmacist or physician for any drug interactions.
Indication
Treatment and of cerebral edema.Reduction of intracranial pressure in neurosurgery.To reduce raised intraocular pressure prior to ophthalmic procedures.To increase urine flow in patients with acute renal failure.Promotion of excretion of toxic materials.Prophylaxis of acute renal failure.
When not to Use
Hypersensitivity to any component of the preparation , Dehydration , Electrolyte depletion and hypovolemia , Suspected intracranial hemorrhage , Congestive heart failure , Acute pulmonary edema , Renal failure, unless a test dose has produced a diuretic response.
Precautions
Precaution
Avoid use in pregnant women. Safe use of mannitol has not been established with respect to effects upon fetal development. It should not be used unless the potential benefits outweigh the possible hazards.
Warnings
Warning 1
Monitor ECG continuously.
Warning 2
Monitor vital signs, level of consciousness, breath sounds and urine output closely during administration.
Warning 3
The patient should have Foley’s catheter in place.
Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.