Levobunolol is a non-cardioselective beta-adrenoceptor blocking agent, equipotent at both beta-1 and beta-2 receptors. Levobunolol does not have significant local anaesthetic (membrane-stabilizing) or intrinsic sympathomimetic activity. The primary mechanism of the ocular hypotensive activity of levobunolol hydrochloride is likely to be a decrease in aqueous humour production. There is little effect on pupil size or accommodation.
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