Betnovate-N Ointment 20g
Betnovate-N Ointment 20g
Betnovate-N Ointment 20g – Betamethasone Valerate & Neomycin Sulphate for Eczema and Skin Infections
Betnovate-N Ointment 20g is a prescription-only, combination topical medication containing Betamethasone Valerate, a potent corticosteroid, and Neomycin Sulphate, a broad-spectrum antibiotic. This dual-action ointment is designed to treat inflammatory and bacterial skin conditions such as eczema, dermatitis, and steroid-responsive dermatoses while preventing or treating secondary bacterial infections.
Prescription Requirement
Requires Prescription: Yes
Active Ingredients (Generic Names)
Betamethasone Valerate – potent topical corticosteroid
Neomycin Sulphate – broad-spectrum bactericidal antibiotic
Therapeutic Class
Topical corticosteroid with antibiotic
Anti-inflammatory and antibacterial skin ointment
Uses / Indications
Betnovate-N Ointment is indicated for:
Eczema and atopic dermatitis
Inflammatory dermatoses responsive to steroids
Psoriasis (less responsive forms)
Skin infections caused or complicated by bacteria
It effectively reduces redness, swelling, and itching, while preventing or treating secondary bacterial infections.
How Betnovate-N Ointment Works
Betamethasone Valerate: Produces a rapid anti-inflammatory response by suppressing the immune activity in the skin, relieving itching, redness, and swelling.
Neomycin Sulphate: Acts as a bactericidal agent against common skin bacteria, preventing infection in damaged or inflamed skin.
The combination ensures both anti-inflammatory and antibacterial action, especially in moist or occluded areas prone to infection.
Dosage & Administration
Apply a thin layer gently over the affected area
Rub in lightly once or twice daily
Maximum duration: 7 days unless otherwise prescribed
Follow your doctor’s instructions carefully
Possible Side Effects
Common and serious side effects may include:
Local hypersensitivity or skin reactions
HPA axis suppression
Cushingoid features (moon face, central obesity)
Growth retardation in children
Osteoporosis, cataract, glaucoma
Hyperglycemia or glucosuria
Weight gain or obesity
Decreased endogenous cortisol levels
Drug Interactions
CYP3A4 inhibitors (e.g., ritonavir, itraconazole) may increase systemic corticosteroid effects
Neomycin Sulphate interacts with other nephrotoxic or ototoxic drugs
When Not to Use Betnovate-N Ointment
Children under 2 years of age
Large areas or prolonged use where systemic absorption may occur
Patients with hypersensitivity to betamethasone, neomycin, or any excipients
Precautions
Avoid occlusive dressings unless instructed by a physician; cleanse skin before applying new dressings
Be cautious in skin folds or warm, moist areas, which can encourage bacterial growth
Monitor for signs of systemic absorption, especially in children
Warnings
Use with caution in patients with history of allergic reactions to corticosteroids or neomycin
Discontinue use and seek medical advice if prolonged diarrhea or abdominal cramps occur
Children are more susceptible to systemic corticosteroid effects due to proportionally higher absorption
Pregnancy & Breastfeeding
Pregnancy Category: Consult your physician before use
Use only if clearly necessary and prescribed
Storage Instructions
Store at room temperature
Protect from direct heat and sunlight
Keep out of reach of children