Otosporin Ear Drops 5ml

It is a bactericidal preparation active against all the pathogens commonly found in bacterial infections of the ear. Polymixin B is bactericidal against a wide range of gram negative bacilli including Pseudomonas Spp., Escherichia coli, Enterobacter Spp., Klebsiella Spp., and Haemophilus influenzae. It exerts a bactericidal effect by binding to acid phospholipids in the cell wall and membranes of the bacterium, thereby rendering ineffective the osmotic barrier normally provided by the cell membrane. This leads to escape of the cell contents and the death of the organism.Neomycin sulphate is bactericidal against a wide range of gram positive and negative bacterial pathogens including Staphylococci, Streptococci, Escherichia, Enterobacter, Klebsiella, Haemophilus, Proteus, Salmonella and Shigella species. It is also active against some strains of the Pseudomonas aeruginosa and against Mycobacterium tuberculosis and Neisseria gonorrhoea. Neomycin exerts its bactericidal effect by interfering with the protein synthesis of susceptible organisms.