SITAZAN 50/500MG TAB (1BOX =14TAB)

Sitagliptin, a DPP-4 inhibitor, enhances the activities of GLP-1 and GIP, which leads to improved glycemic control in patients with type 2 diabetes. It achieves this by reducing fasting and post-prandial blood glucose levels. On the other hand, Metformin, a guanidine derivative, possesses antimicrobial properties. It reduces glucose production by the liver, increases glucose uptake by skeletal muscle, and enhances glucose uptake and utilization by anaerobic pathways in tissues such as the kidney. Additionally, it diminishes hunger and induces weight loss in some individuals. The combination of Sitagliptin 50mg and Metformin 500mg is typically prescribed to adults with type 2 diabetes when diet and exercise alone are not sufficient to manage blood sugar levels. It's worth noting that this description is a simplified overview, and the actual mechanisms of action for these drugs are more intricate and are still being researched.

DPP-4 Inhibitors

Tablet

Unveiling its multifaceted uses and transformative applications as follows:

• Treatment of type 2 diabetes mellitus
• Enhances the actions of incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)
• Delays the absorption of glucose in the blood stream
• Ensures gradual release of glucose and stimulates the pancreas to produce insulin
• Metformin acts by reducing the excessive secretion of glucose from the liver
• Downregulates glucose absorption in the gastrointestinal tract
• Increases the uptake of glucose by skeletal muscle
• Reduced chances of diabetic complications like neuropathy, retinopathy, and nephropathy

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For treating type 2 diabetes, the recommended dose of Sitagliptin is 50mg to be taken once a day.
• The recommended dose of Metformin ranges from 500mg to 2000mg depending on the severity of the patient's insulin resistance and their response to the medication.
• It is crucial to adhere to the prescription provided to you by your doctor.
• Please consult your doctor for any specific dosage instructions pertaining to your individualized health needs and medical history.