Tri-Melasin Cream 30g

Tri-Melasin Cream 30g

Generic Name: Fluocinolone Acetonide 0.01% + Hydroquinone 4% + Tretinoin 0.05%
Dosage Form: Topical Cream
Therapeutic Category: Triple Combination Depigmenting Therapy
Prescription Required: Yes

Tri-Melasin Cream 30g – Triple Combination Treatment for Melasma

Tri-Melasin Cream 30g is a prescription-strength triple combination cream formulated for the short-term treatment of moderate to severe facial melasma. It combines a corticosteroid (Fluocinolone Acetonide), a skin-lightening agent (Hydroquinone), and a topical retinoid (Tretinoin) to effectively reduce hyperpigmentation, dark patches, and uneven skin tone.

This dermatologist-recommended formulation targets excess melanin production while improving skin renewal and reducing inflammation.

Active Ingredients & How They Work
Fluocinolone Acetonide 0.01% (Mild Corticosteroid)

Reduces skin inflammation and redness

Minimizes irritation caused by other active ingredients

Calms inflamed or sensitive skin

Hydroquinone 4% (Depigmenting Agent)

Inhibits melanin synthesis

Blocks tyrosinase activity responsible for pigment production

Lightens dark spots, melasma patches, and discoloration

Tretinoin 0.05% (Topical Retinoid)

Increases skin cell turnover

Promotes exfoliation of pigmented skin cells

Enhances penetration of hydroquinone

Improves skin texture and tone

Together, these three agents work synergistically to treat chloasma, hyperpigmentation, sun spots, and hormonal pigmentation.

Indications

Tri-Melasin Cream is indicated for:

Short-term treatment of moderate to severe melasma of the face

Hyperpigmentation disorders

Uneven skin tone caused by sun damage or hormonal changes

Dosage & Administration

Adults:

Apply once or twice daily for a minimum of 8 weeks, or as directed by your dermatologist.

Children: Not recommended.

Apply a thin layer only to affected areas on clean, dry skin.

Possible Side Effects

Erythema (redness)

Skin irritation or burning sensation

Hyperpigmentation or hypopigmentation

Mild peeling

If severe irritation or allergic reaction occurs, discontinue use and consult your physician.

Drug Interactions

Use cautiously with:

Keratolytics

Other exfoliating or irritating topical agents

Avoid combining with strong chemical peels or abrasive treatments unless advised by a dermatologist.

When Not to Use

Do NOT use Tri-Melasin Cream if:

You are hypersensitive to Fluocinolone, Hydroquinone, Tretinoin, or any component of the formulation

You are pregnant or planning pregnancy

Important Warnings & Precautions
Sun Protection Required

This medication increases photosensitivity.

Avoid direct sunlight and artificial UV exposure

Use broad-spectrum sunscreen (minimum SPF 30)

Wear protective clothing

Dermatologist Supervision

Use only on areas evaluated by a dermatologist.

For individual brown lesions (lentigines), treatment duration should not exceed 3 months.

Any lesion that darkens, thickens, enlarges, or recurs should be reassessed to rule out malignancy.

Medical Conditions

Inform your doctor if you:

Have liver or kidney disease

Are allergic to any medications

Pregnancy Warning

This medication may harm an unborn baby.
Do NOT use during pregnancy.

Storage Instructions

Store at room temperature

Keep away from direct light and heat

Keep out of reach of children